USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1
Abstract PD-L1(CD274) is a well-known immunosuppressive molecule, which confers immunoescape features to cancer cells and has become one of the major targets in cancer immunotherapies.Understanding the regulatory mechanisms that control PD-L1 protein expression is important for guiding immune checkpoint blockade therapy.Here, we showed Ski de fond